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Computer Tomograph (CT) imaging of mandibular anatomical substrate in animal model restored with nanostructured hydroxyapatite compounds

Identifieur interne : 001297 ( Main/Exploration ); précédent : 001296; suivant : 001298

Computer Tomograph (CT) imaging of mandibular anatomical substrate in animal model restored with nanostructured hydroxyapatite compounds

Auteurs : R. Ciuluvic [Roumanie] ; S. Gr Dinaru [Roumanie] ; M. Popescu [Roumanie] ; Rm Piticescu [Roumanie] ; R. Cergan [Roumanie]

Source :

RBID : PMC:4397532

Abstract

Introduction: This study was meant to test a new type of bone graft on an animal model. This material was a nanostructured hydroxyapatite.

Materials and Methods: the study was conducted according to Ethic Committee Regulation on animal model (Oryctolagus cuniculus – rabbit) between August and November 2014, at “Carol Davila” University of Medicine and Pharmacy, Bucharest. The animals were tested by using a CT at the level of the mandible before and after using the nanostructured hydroxyapatite.

Results: The animals were CT scanned at 1, 2 and respectively 3 months, noticing a growth of the mandibular bone density. After 3 months, a bone density equal with the density of the healthy bone was noticed.

Conclusions: The use of the bone graft could be a viable alternative to available materials. The advantage was that bone recovery had a density similar to the density of the healthy bone and the cost of production was low because it was made out of Calcium azotate and monobasic ammonium phosphate.


Url:
PubMed: 25914749
PubMed Central: 4397532


Affiliations:


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<bold>Introduction:</bold>
This study was meant to test a new type of bone graft on an animal model. This material was a nanostructured hydroxyapatite.</p>
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<bold>Materials and Methods:</bold>
the study was conducted according to Ethic Committee Regulation on animal model (Oryctolagus cuniculus – rabbit) between August and November 2014, at “Carol Davila” University of Medicine and Pharmacy, Bucharest. The animals were tested by using a CT at the level of the mandible before and after using the nanostructured hydroxyapatite.</p>
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The animals were CT scanned at 1, 2 and respectively 3 months, noticing a growth of the mandibular bone density. After 3 months, a bone density equal with the density of the healthy bone was noticed.</p>
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The use of the bone graft could be a viable alternative to available materials. The advantage was that bone recovery had a density similar to the density of the healthy bone and the cost of production was low because it was made out of Calcium azotate and monobasic ammonium phosphate.</p>
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